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Binding potencies (Ki-nM) of ligands for the cloned k, d, and µ opioid... |  Download Table
Binding potencies (Ki-nM) of ligands for the cloned k, d, and µ opioid... | Download Table

An updated assessment of the translational promise of G-protein-biased kappa  opioid receptor agonists to treat pain and other indications without  debilitating adverse effects - ScienceDirect
An updated assessment of the translational promise of G-protein-biased kappa opioid receptor agonists to treat pain and other indications without debilitating adverse effects - ScienceDirect

Opportunities for targeting the BBB to optimize CNS drug delivery |  Download Scientific Diagram
Opportunities for targeting the BBB to optimize CNS drug delivery | Download Scientific Diagram

Strategies to facilitate the discovery of novel CNS PET ligands | EJNMMI  Radiopharmacy and Chemistry | Full Text
Strategies to facilitate the discovery of novel CNS PET ligands | EJNMMI Radiopharmacy and Chemistry | Full Text

Cellular and molecular mechanisms involved in Multiple Sclerosis CNS... |  Download Scientific Diagram
Cellular and molecular mechanisms involved in Multiple Sclerosis CNS... | Download Scientific Diagram

Insights into the promising prospect of pharmacological approaches  targeting mitochondrial dysfunction in major human diseases: At a glance -  ScienceDirect
Insights into the promising prospect of pharmacological approaches targeting mitochondrial dysfunction in major human diseases: At a glance - ScienceDirect

Cureus | A Rare Presentation of Primary Central Nervous System Lymphoma in  an Immunocompetent Patient | Article
Cureus | A Rare Presentation of Primary Central Nervous System Lymphoma in an Immunocompetent Patient | Article

Frontiers | Infection in the Developing Brain: The Role of Unique Systemic  Immune Vulnerabilities
Frontiers | Infection in the Developing Brain: The Role of Unique Systemic Immune Vulnerabilities

Frontiers | Neuroinflammation in Autoimmune Disease and Primary Brain  Tumors: The Quest for Striking the Right Balance
Frontiers | Neuroinflammation in Autoimmune Disease and Primary Brain Tumors: The Quest for Striking the Right Balance

Characterization of Pyrrolidinyl-hexahydro-pyranopiperazines as a Novel  Kappa Opioid Receptor Agonist Scaffold | ACS Chemical Neuroscience
Characterization of Pyrrolidinyl-hexahydro-pyranopiperazines as a Novel Kappa Opioid Receptor Agonist Scaffold | ACS Chemical Neuroscience

Frontiers | Uncovering incontinentia pigmenti: From DNA sequence to  pathophysiology
Frontiers | Uncovering incontinentia pigmenti: From DNA sequence to pathophysiology

Brain Sciences | Free Full-Text | Understanding the Neurotrophic Virus  Mechanisms and Their Potential Effect on Systemic Lupus Erythematosus  Development
Brain Sciences | Free Full-Text | Understanding the Neurotrophic Virus Mechanisms and Their Potential Effect on Systemic Lupus Erythematosus Development

Primary CNS DLBCL. Lymphoma cells are round to oval and contain... |  Download Scientific Diagram
Primary CNS DLBCL. Lymphoma cells are round to oval and contain... | Download Scientific Diagram

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist  Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical  Neuroscience
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience

Diagnostics | Free Full-Text | Primary Central Nervous System Lymphomas: A  Diagnostic Overview of Key Histomorphologic, Immunophenotypic, and Genetic  Features
Diagnostics | Free Full-Text | Primary Central Nervous System Lymphomas: A Diagnostic Overview of Key Histomorphologic, Immunophenotypic, and Genetic Features

Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico  Characterization of a Novel Kappa-Opioid Receptor Antagonist
Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico Characterization of a Novel Kappa-Opioid Receptor Antagonist

PDF) Kappa Index Versus CSF Oligoclonal Bands in Predicting Multiple  Sclerosis and Infectious/Inflammatory CNS Disorders
PDF) Kappa Index Versus CSF Oligoclonal Bands in Predicting Multiple Sclerosis and Infectious/Inflammatory CNS Disorders

Pharmaceutics | Free Full-Text | Transport Mechanisms at the  Blood–Brain Barrier and in Cellular Compartments of the Neurovascular  Unit: Focus on CNS Delivery of Small Molecule Drugs
Pharmaceutics | Free Full-Text | Transport Mechanisms at the Blood–Brain Barrier and in Cellular Compartments of the Neurovascular Unit: Focus on CNS Delivery of Small Molecule Drugs

Frontiers | The Role of the Kappa Opioid System in Comorbid Pain and  Psychiatric Disorders: Function and Implications
Frontiers | The Role of the Kappa Opioid System in Comorbid Pain and Psychiatric Disorders: Function and Implications

Institutionen för klinisk neurovetenskap | Karolinska Institutet
Institutionen för klinisk neurovetenskap | Karolinska Institutet

Signaling pathways in brain tumors and therapeutic interventions | Signal  Transduction and Targeted Therapy
Signaling pathways in brain tumors and therapeutic interventions | Signal Transduction and Targeted Therapy

Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural  Refinement and Evaluation of CNS Clearance | ACS Chemical Neuroscience
Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural Refinement and Evaluation of CNS Clearance | ACS Chemical Neuroscience

Kappa opioid receptor activation increases thermogenic energy expenditure  which drives increased feeding - ScienceDirect
Kappa opioid receptor activation increases thermogenic energy expenditure which drives increased feeding - ScienceDirect

In vivo mapping of a GPCR interactome using knockin mice | PNAS
In vivo mapping of a GPCR interactome using knockin mice | PNAS

Frontiers | GFAPδ: A Promising Biomarker and Therapeutic Target in  Glioblastoma
Frontiers | GFAPδ: A Promising Biomarker and Therapeutic Target in Glioblastoma