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Discovery and Binding Mechanism of Pyrazoloisoquinoline-Based Novel  β-Arrestin Inverse Agonists of the Kappa-Opioid Receptor | Journal of  Medicinal Chemistry
Discovery and Binding Mechanism of Pyrazoloisoquinoline-Based Novel β-Arrestin Inverse Agonists of the Kappa-Opioid Receptor | Journal of Medicinal Chemistry

The role of p300/CREB binding protein (CBP)-associated factor (PCAF) in...  | Download Scientific Diagram
The role of p300/CREB binding protein (CBP)-associated factor (PCAF) in... | Download Scientific Diagram

Kappa opioid receptor (KOR) modulation of dopamine in the cortex and... |  Download Scientific Diagram
Kappa opioid receptor (KOR) modulation of dopamine in the cortex and... | Download Scientific Diagram

Brain Sciences | Free Full-Text | Shared Mechanisms of GABAergic and  Opioidergic Transmission Regulate Corticolimbic Reward Systems and  Cognitive Aspects of Motivational Behaviors
Brain Sciences | Free Full-Text | Shared Mechanisms of GABAergic and Opioidergic Transmission Regulate Corticolimbic Reward Systems and Cognitive Aspects of Motivational Behaviors

Frontiers | The Role of the Kappa Opioid System in Comorbid Pain and  Psychiatric Disorders: Function and Implications
Frontiers | The Role of the Kappa Opioid System in Comorbid Pain and Psychiatric Disorders: Function and Implications

Development of κ Opioid Receptor Antagonists | Journal of Medicinal  Chemistry
Development of κ Opioid Receptor Antagonists | Journal of Medicinal Chemistry

JCI Insight - Kappa opioid receptor signaling protects cartilage tissue  against posttraumatic degeneration
JCI Insight - Kappa opioid receptor signaling protects cartilage tissue against posttraumatic degeneration

Full article: The κ-Opioid Receptor Agonist U50488H Ameliorates Neuropathic  Pain Through the Ca2+/CaMKII/CREB Pathway in Rats
Full article: The κ-Opioid Receptor Agonist U50488H Ameliorates Neuropathic Pain Through the Ca2+/CaMKII/CREB Pathway in Rats

IJMS | Free Full-Text | The Downregulation of Opioid Receptors and  Neuropathic Pain
IJMS | Free Full-Text | The Downregulation of Opioid Receptors and Neuropathic Pain

JCI Insight - Kappa opioid receptor signaling protects cartilage tissue  against posttraumatic degeneration
JCI Insight - Kappa opioid receptor signaling protects cartilage tissue against posttraumatic degeneration

Full article: The κ-Opioid Receptor Agonist U50488H Ameliorates Neuropathic  Pain Through the Ca2+/CaMKII/CREB Pathway in Rats
Full article: The κ-Opioid Receptor Agonist U50488H Ameliorates Neuropathic Pain Through the Ca2+/CaMKII/CREB Pathway in Rats

Model by which the dynorphin/kappa system could counteract... | Download  Scientific Diagram
Model by which the dynorphin/kappa system could counteract... | Download Scientific Diagram

Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain |  Journal of Neuroscience
Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain | Journal of Neuroscience

κ-Opioid Receptor Agonist Ameliorates Postoperative Neurocognitive Disorder  by Activating the Ca2+/CaMKII/CREB Pathway
κ-Opioid Receptor Agonist Ameliorates Postoperative Neurocognitive Disorder by Activating the Ca2+/CaMKII/CREB Pathway

The many faces of CREB - ScienceDirect
The many faces of CREB - ScienceDirect

Frontiers | Mu-opioid receptor and receptor tyrosine kinase crosstalk:  Implications in mechanisms of opioid tolerance, reduced analgesia to  neuropathic pain, dependence, and reward
Frontiers | Mu-opioid receptor and receptor tyrosine kinase crosstalk: Implications in mechanisms of opioid tolerance, reduced analgesia to neuropathic pain, dependence, and reward

Systemic kappa opioid receptor antagonism accelerates reinforcement  learning via augmentation of novelty processing in male mice |  Neuropsychopharmacology
Systemic kappa opioid receptor antagonism accelerates reinforcement learning via augmentation of novelty processing in male mice | Neuropsychopharmacology

A proposed mechanism for the adenosine A2AR agonist mediated activation...  | Download Scientific Diagram
A proposed mechanism for the adenosine A2AR agonist mediated activation... | Download Scientific Diagram

Kappa‐Opioid Antagonists for Psychiatric Disorders: From Bench to Clinical  Trials - Carlezon - 2016 - Depression and Anxiety - Wiley Online Library
Kappa‐Opioid Antagonists for Psychiatric Disorders: From Bench to Clinical Trials - Carlezon - 2016 - Depression and Anxiety - Wiley Online Library

Desipramine Reduces Stress-Activated Dynorphin Expression and CREB  Phosphorylation in NAc Tissue | Molecular Pharmacology
Desipramine Reduces Stress-Activated Dynorphin Expression and CREB Phosphorylation in NAc Tissue | Molecular Pharmacology

Full article: The κ-Opioid Receptor Agonist U50488H Ameliorates Neuropathic  Pain Through the Ca2+/CaMKII/CREB Pathway in Rats
Full article: The κ-Opioid Receptor Agonist U50488H Ameliorates Neuropathic Pain Through the Ca2+/CaMKII/CREB Pathway in Rats

Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural  Refinement and Evaluation of CNS Clearance | ACS Chemical Neuroscience
Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural Refinement and Evaluation of CNS Clearance | ACS Chemical Neuroscience

κ-Opioid receptor agonist U50488H ameliorates neuropathic | JIR
κ-Opioid receptor agonist U50488H ameliorates neuropathic | JIR

Gene Expression Profiling of Facilitated L-LTP in VP16-CREB Mice Reveals  that BDNF Is Critical for the Maintenance of LTP and Its Synaptic Capture:  Neuron
Gene Expression Profiling of Facilitated L-LTP in VP16-CREB Mice Reveals that BDNF Is Critical for the Maintenance of LTP and Its Synaptic Capture: Neuron